doi: 10.7164/antibiotics.28.185.
Metabolic products of microorganisms 137. Rinamycin, a new inhibitor of RNA synthesis
- PMID: 805116
- DOI: 10.7164/antibiotics.28.185
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Metabolic products of microorganisms 137. Rinamycin, a new inhibitor of RNA synthesis
J Antibiot (Tokyo).
1975 Mar.
Free article
Abstract
A new antibiotic rinamycin was isolated from the culture mycelium of a streptomycete designated as Streptomyces venezuelae TU 1102. The antibiotic was obtained as a honey-coloured powder having the tentative molecular formula C20H55N08. It exhibits a significant inhibition of fungi, yeasts, gram-negative bacteria. The primary site of action of the antibiotic was suggested to be the RNA metabolism of rinamycin-sensitive cells.
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