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Comparative Study
. 1994 Sep;68(9):6057-8.
doi: 10.1128/JVI.68.9.6057-6058.1994.

Cell culture adaptation of astrovirus involves a deletion

M M Willcocks  1 , N Ashton, J B Kurtz, W D Cubitt, M J Carter
Affiliations
Comparative Study

Cell culture adaptation of astrovirus involves a deletion

M M Willcocks et al. J Virol. 1994 Sep.

Abstract

Astroviruses have been adapted to culture by serial blind passage in primary human embryo cells. All viruses thus adapted possess a 45-nucleotide deletion relative to fecal viruses or isolates made in CaCo-2 cells; this deletion may be responsible for the change in host cell range.

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