Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1994 Sep;192(3):625-30.
doi: 10.1148/radiology.192.3.8058925.

Coronary artery disease: prediction with in vitro electron beam CT

S L Mautner  1 , G C Mautner, J Froehlich, I M Feuerstein, M A Proschan, W C Roberts, J L Doppman
Affiliations

Coronary artery disease: prediction with in vitro electron beam CT

S L Mautner et al. Radiology. 1994 Sep.

Abstract

Purpose: To investigate the potential to predict coronary artery disease with electron beam computed tomography (CT).

Materials and methods: Fifty heart specimens were examined with electron beam CT and histomorphometric techniques to measure calcific deposits as a percentage of blockage.

Results: In group A specimens (from cadavers of patients with symptomatic coronary artery disease), calcific deposits were identified at electron beam CT in 41% (584 of 1,426) of all segments of coronary arteries; in group B specimens (with asymptomatic coronary artery disease), in 24% (369 of 1,535) of all segments; and in the normal control specimens, in 4% (47 of 1,337) of all segments; segments (group A vs control specimens, P < .0001; group B vs control specimens, P = .02). On the basis of logistic regression analysis, coronary artery disease would be predicted if the average electron beam CT calcium score exceeds 0.32. The sensitivity and specificity of electron beam CT in the detection of calcific deposits per coronary artery was 94% and 76%, respectively.

Conclusion: The electron beam CT calcium score appears to be an effective predictor of coronary artery disease.

PubMed Disclaimer

Comment in

  • Coronary artery calcification.
    Doherty TM, Detrano RC. Doherty TM, et al. Radiology. 1995 May;195(2):576-7. doi: 10.1148/radiology.195.2.7598765. Radiology. 1995. PMID: 7598765 No abstract available.

Publication types