Olfactory neuroblastoma. A report of 5 cases

Abstract

The present paper presents 5 cases of olfactory neuroblastoma (NO), showing the problems concerning the diagnosis and treatment. The olfactory neuroblastoma is a rare tumor that represents 1 to 5% of the malignant tumors of the nasal cavity. The wide range of the patient's age associated with variety clinical and histological findings, made the diagnosis often difficult.

Conclusions: neuroblastoma has a difficult diagnosis; the histologic diagnosis should always be complemented by the immunohistochemical investigation; surgical resection with adequate margins is the first treatment on resectable lesions.