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Comparative Study
. 1975;17(2):161-3.
doi: 10.1007/BF02547288.

Mineralization of dentin, bone and tendon in vitro

C V DeSteno, F Fragin, W T Butler
Comparative Study

Mineralization of dentin, bone and tendon in vitro

C V DeSteno et al. Calcif Tissue Res. 1975.

Abstract

Bovin dentin, bone and tendon slices, and rat bone, readily mineralize to variable degrees after demineralization by (EDTA) at pH 7.4, but they fail to mineralize after dimeralzation with acetic acid (HAc) at pH3.0. The demineralized dentin, but neither bone nor tendon, contained organically bound phosphate. The EDTA-demineralized dentin contained less phosphate than HAc-demineralized dentin. HAc-demineralized rat dentin contained high levels of phosphate. Since the EDTA- and HAc-demineralized rat dentin contained widely different levels of phosphate, yet both mineralized, it was concluded that phosphoprotein had little effect on nucleation. The reason why HAc-demineralized tissue other than rat dentin failed to nucleate and mineralize was not clarified.

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References

    1. Biochem Biophys Res Commun. 1972 Sep 26;48(6):1656-62 - PubMed
    1. Ala J Med Sci. 1973 Jan;10(1):60-6 - PubMed
    1. Biochim Biophys Acta. 1972 Jan 26;257(1):167-71 - PubMed
    1. Calcif Tissue Res. 1975;17(2):151-9 - PubMed
    1. Biochim Biophys Acta. 1972 Feb 29;257(2):404-13 - PubMed

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