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Case Reports
. 1994 Jul 11;156(28):4151-2.

[Allergic myocarditis in clozapine treatment]

[Article in Danish]
V E Jensen  1 , O Gøtzsche
Affiliations
  • PMID: 8066913
Case Reports

[Allergic myocarditis in clozapine treatment]

[Article in Danish]
V E Jensen et al. Ugeskr Laeger. .

Abstract

Clozapine is a high-dose neuroleptic, which is recommended only for those cases in which patients have failed to respond adequately to standard antipsychotic drugs. This report describes a 45 year old man with ischaemic heart disease who died of cardiogenic shock 11 days after starting treatment with clozapine. Autopsy showed apart from coronary atherosclerosis and interstitial fibrosis a considerable infiltration of eosinophilic granulocytes in the myocardium suggesting myocarditis as the cause of death.

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