Molecular characterization of the gene encoding high-level mupirocin resistance in Staphylococcus aureus J2870
- PMID: 8067768
- PMCID: PMC188182
- DOI: 10.1128/AAC.38.5.1205
Molecular characterization of the gene encoding high-level mupirocin resistance in Staphylococcus aureus J2870
Abstract
The nucleotide sequence of the ileS gene conferring high-level resistance to mupirocin in Staphylococcus aureus J2870 has been determined. The gene sequence is substantially different from that of the native ileS gene of S. aureus, indicating that high-level resistance to mupirocin results from the acquisition of a novel ileS gene.
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