Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1978 Oct 7;2(8093):763-4.
doi: 10.1016/s0140-6736(78)92650-8.

Diagnosis of protein-losing enteropathy by gastrointestinal clearance of alpha1-antitrypsin

J J Bernier, C Florent, C Desmazures, C Aymes, C L'Hirondel

Diagnosis of protein-losing enteropathy by gastrointestinal clearance of alpha1-antitrypsin

J J Bernier et al. Lancet. .

Abstract

Alpha1-antitrypsin was assessed, in 10 patients with protein-losing enteropathy and 13 control subjects, as an endogenous marker of plasma-protein loss into the gastrointestinal tract. Both faecal alpha1-A.T. concentrations and faecal alpha1-A.T. clearance were significantly higher in patients than in controls. Wtih clearance there was no overlap between the groups. Over 10 days the normal gastrointestinal clearance of alpha1-A.T. was 3.07 +/- 2.25 (S.D.) ml/day. Measurement of alpha1-A.T. clearance is easy and requires no radioisotopes.

PubMed Disclaimer

MeSH terms

Substances

LinkOut - more resources