Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1975;27(2):163-6.
doi: 10.1007/BF00273333.

Population and family studies on carbonic anhydrase II polymorphism in Gambia, West Africa

S Welch

Population and family studies on carbonic anhydrase II polymorphism in Gambia, West Africa

S Welch. Humangenetik. 1975.

Abstract

614 individuals from the village of Keneba in Gambia (West Africa) have been typed for red cell Carbonic Anhydrase II using cellulose acetate electrophoresis followed by detection of the enzyme with the fluorogenic substrate fluorescein diacetate. Three phenotypes were found; 479 CAII 1 (80.94%), 107 CAII 2-1 (17.43%), and 10 CAII 2 (1.63%). The gene frequencies of the 2 autosomal alleles responsible for the electrophoretically distinguishable polymorphism were CAII 1 0.897 and CAII 2 0.103. A study of 72 families confirmed the simple Menedelian co-dominant inheritance.

PubMed Disclaimer

References

    1. Ann Hum Genet. 1974 Oct;38(2):155-62 - PubMed
    1. J Biol Chem. 1972 Jun 25;247(12):3761-6 - PubMed
    1. Biochem Genet. 1967 Sep;1(2):171-95 - PubMed
    1. Am J Hum Genet. 1973 Jan;25(1):29-35 - PubMed
    1. Biochem Genet. 1973 Dec;10(4):399-408 - PubMed