Structural homogeneity of human subacute sclerosing panencephalitis antibodies
- PMID: 807623
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Structural homogeneity of human subacute sclerosing panencephalitis antibodies
J Immunol.
1975 Jul.
Abstract
Three homogeneous immunoglobulin fractions were isolated from the serum of a patient with subacute sclerosing panencephalitis (SSPE). All three fractions reacted in immunodiffusion with measles and SSPE virus preparations. The amino-terminal sequence of the light and heavy chains of one of the antibody fractions was determined by automated Edman degradation. A single amino acid residue was obtained at every step, confirming the homogeneity of this human antibody.
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