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Review
. 1994 Sep;56(3):399-406.
doi: 10.1002/jlb.56.3.399.

Biology of the mononuclear phagocyte system of the central nervous system and HIV infection

V H Perry  1 , L J Lawson, D M Reid
Affiliations
Review

Biology of the mononuclear phagocyte system of the central nervous system and HIV infection

V H Perry et al. J Leukoc Biol. 1994 Sep.

Abstract

Infection of the central nervous system by HIV-1 results in widespread neuropathology and neurological symptoms. The cells infected in the brain belong to the mononuclear phagocyte lineage. We review aspects of the biology of the macrophage populations associated with the central nervous system and consider their distribution, phenotype, and kinetics in relation to HIV pathology.

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