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Case Reports
. 1994 Jun;34(6):1078-80; discussion 1080-1.
doi: 10.1227/00006123-199406000-00021.

Successful adoptive immunotherapy with lymphokine-activated killer cells in the treatment of medulloblastoma disseminated via cerebrospinal fluid: case report

A Silvani  1 , A Salmaggi, G Parmiani, A Boiardi
Affiliations
Case Reports

Successful adoptive immunotherapy with lymphokine-activated killer cells in the treatment of medulloblastoma disseminated via cerebrospinal fluid: case report

A Silvani et al. Neurosurgery. 1994 Jun.

Abstract

We report the case of a girl who developed cerebellar medulloblastoma at the age of 12 years and in whom, 4 years after surgical removal and radiotherapy, neoplastic dissemination via the cerebrospinal fluid took place. After only partially effective systemic and intrathecal chemotherapy, an intrathecal administration of lymphokine-activated killer cells and recombinant interleukin-2 allowed complete clinical recovery persisting after a follow-up of 30 months.

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