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Review
. 1994:396:11-7.
doi: 10.1111/j.1651-2227.1994.tb13234.x.

Platelet-activating factor, tumor necrosis factor, hypoxia and necrotizing enterocolitis

W Hsueh  1 , M S Caplan, X Sun, X Tan, W MacKendrick, F Gonzalez-Crussi
Affiliations
Review

Platelet-activating factor, tumor necrosis factor, hypoxia and necrotizing enterocolitis

W Hsueh et al. Acta Paediatr Suppl. 1994.

Abstract

The pathogenesis of necrotizing enterocolitis (NEC) is poorly understood. We have established several animal models of NEC by using a combination of various stimuli and stress, including endotoxin, PAF, TNF, and hypoxia. We discuss the mechanism of their actions and the possible roles of these factors in the pathogenesis of human NEC.

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