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Review
. 1994 Jun;2(6):202-6.
doi: 10.1016/0966-842x(94)90112-i.

The role of cell-mediated immunity in candidiasis

P L Fidel Jr  1 , J D Sobel
Affiliations
Review

The role of cell-mediated immunity in candidiasis

P L Fidel Jr et al. Trends Microbiol. 1994 Jun.

Abstract

Clinical observations and animal models show that cell-mediated immunity (CMI) is an important host defense mechanism against Candida albicans infections. In HIV-infected patients, a switch from TH1- to TH2-type CMI responses correlates with the progression to AIDS, and may also increase susceptibility to mucosal candidiasis.

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