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Clinical Trial
. 1975 Aug 30;105(35):1123-5.

[Prevention of infection in patients with agranulocytosis through isolation and whole-body decontamination]

[Article in German]
M Fopp, A Gasser, B Eigenmann, W F Jungi, G Meuret, H J Senn
  • PMID: 808849
Clinical Trial

[Prevention of infection in patients with agranulocytosis through isolation and whole-body decontamination]

[Article in German]
M Fopp et al. Schweiz Med Wochenschr. .

Abstract

During induction chemotherapy 21 patients with acute myelogenous leukemia and agranulocytosis were prophylactically isolated either in reverse isolation (group A) or in sterile plastic-tent isolators with laminar air flow (Life Islands, group B). Patients of group B also received whole-body decontamination and sterile food. Life threatening septicemias were seen only in patients in reverse isolation. Granulocyte transfusions were highly successful in reducing infection-related mortality in group A. Seven additional patients with agranulocytosis of varying origin (group C) were protected in the Life Islands as effectively as the patients with acute leukemia.

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