doi: 10.1016/0006-8993(75)90352-2.
Ontogeny of multiple forms of monoamine oxidase in mouse brain
- PMID: 809102
- DOI: 10.1016/0006-8993(75)90352-2
Item in Clipboard
Ontogeny of multiple forms of monoamine oxidase in mouse brain
Brain Res.
.
Abstract
MAO activities in mouse brain responsible for deamination of serotonin (5-HT) and p-dimethylaminobenzylamine (DAB) were found to follow different postnatal developmental patterns. MAO activity which deaminated 5-HT reached adult levels 15 days after birth. At this age the capacity of brain to deaminate DAB was only 50% of adult levels and did not develop fully until after the 45th postnatal day. Inhibitor studies with Deprenil and clorgyline indicated that the deamination of the two substrates was due to different forms of MAO and that these forms were similar to type A and type B MAO described previously in rat brain.
Similar articles
-
Developmental changes in the activity and substrate specificities of mouse brain monoamine oxidase.Neurochem Res. 1984 May;9(5):595-606. doi: 10.1007/BF00964506. Neurochem Res. 1984. PMID: 6472564
-
Preferential deamination of dopamine by an A type monoamine oxidase in rat brain.Naunyn Schmiedebergs Arch Pharmacol. 1976;292(1):9-14. doi: 10.1007/BF00506483. Naunyn Schmiedebergs Arch Pharmacol. 1976. PMID: 934359
-
Effects of monoamine oxidase inhibition by clorgyline, deprenil or tranylcypromine on 5-hydroxytryptamine concentrations in rat brain and hyperactivity following subsequent tryptophan administration.Br J Pharmacol. 1975 Nov;55(3):415-22. doi: 10.1111/j.1476-5381.1975.tb06946.x. Br J Pharmacol. 1975. PMID: 1203627 Free PMC article.
-
Are there MAO inhibitors specific for dopamine metabolism?Adv Biochem Psychopharmacol. 1977;16:349-58. Adv Biochem Psychopharmacol. 1977. PMID: 329649 Review. No abstract available.
-
Developmental characteristics of monamine oxidase.Comp Biochem Physiol C Comp Pharmacol. 1975 Aug 1;51(2):143-51. doi: 10.1016/0306-4492(75)90052-0. Comp Biochem Physiol C Comp Pharmacol. 1975. PMID: 241572 Review. No abstract available.
Cited by
-
Characteristics of enzymes forming 3-methoxy-4-hydroxyphenylethyleneglycol (MOPEG) in brain.Neurochem Res. 1976 Oct;1(5):525-40. doi: 10.1007/BF00964213. Neurochem Res. 1976. PMID: 24271656
-
Genotype dependence of monoamine oxidase in inbred strains of mice.Experientia. 1976 Aug 15;32(8):979-80. doi: 10.1007/BF01933922. Experientia. 1976. PMID: 955032
-
Developmental changes in human dopamine neurotransmission: cortical receptors and terminators.BMC Neurosci. 2012 Feb 15;13:18. doi: 10.1186/1471-2202-13-18. BMC Neurosci. 2012. PMID: 22336227 Free PMC article.
-
Developmental changes in the activity and substrate specificities of mouse brain monoamine oxidase.Neurochem Res. 1984 May;9(5):595-606. doi: 10.1007/BF00964506. Neurochem Res. 1984. PMID: 6472564
-
Monoamine oxidase in young and adult rat brain capillaries.J Neural Transm. 1984;60(3-4):239-45. doi: 10.1007/BF01249096. J Neural Transm. 1984. PMID: 6527138
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
