[The neurovirulence of variants of the Langat TP-21 virus in experiments on different species of lower monkeys]

Abstract

Neurovirulence of the attenuated strains of Langat TP-21 virus was tested in monkeys of 5 species: M. mulatta, M. fascicularis, M. nemestrina, C. aethiops, and P. hamadryas. The individual susceptibility of the animals to the infection varied but there was no difference in species susceptibility. The monkeys were more susceptible to intraspinal than to intrathalamic inoculations. The animals not adapted to the laboratory conditions were more susceptible to infection than the adapted ones. The lesions in the spinal cord were the most informative pathomorphological data for differentiation of attenuated strains of Langat TP-21 virus.