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Case Reports
. 1993 Jan 16;341(8838):149-50.
doi: 10.1016/0140-6736(93)90008-5.

Hepatitis E virus transmission to a volunteer

A Chauhan  1 , S Jameel, J B Dilawari, Y K Chawla, U Kaur, N K Ganguly
Affiliations
Case Reports

Hepatitis E virus transmission to a volunteer

A Chauhan et al. Lancet. .

Abstract

Hepatitis E virus (HEV) causes an enteric non-A, non-B hepatitis. The disease occurs in epidemic settings and sporadically, and viral transmission is thought to be faecal-oral. We present here a single volunteer study of HEV transmission followed by disease. Clinical and biochemical features of the infection correlated with HEV detection in the stools and sera by reverse transcription/polymerase chain amplification. IgG antibody has persisted for 2 years. The presence of HEV in serum before clinical signs appeared suggests that in endemic areas sporadic transmission of HEV may also occur parenterally.

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