Review
doi: 10.1016/0300-9629(93)90439-b.
The development and function of the Drosophila CNS midline cells
Affiliations
- PMID: 8097144
- DOI: 10.1016/0300-9629(93)90439-b
Item in Clipboard
Review
The development and function of the Drosophila CNS midline cells
Comp Biochem Physiol Comp Physiol.
1993 Mar.
Abstract
1. The midline cells of the Drosophila embryonic CNS comprise a discrete neuroanatomical structure consisting of a small subset of neurons and glia. 2. Developmental commitment of the CNS midline cells requires the action of dorsal/ventral patterning genes. 3. The single-minded gene encodes a basic-helix-loop-helix transcription factor and acts as a master regulator for the CNS midline lineage. 4. A number of different transcription factors and proteins involved in cell-cell interactions are necessary for the differentiation of midline neurons and glia. 5. CNS midline cells have important functions in the formation of the ventral epidermis and axon commissures.
Similar articles
-
Specification of the Drosophila CNS midline cell lineage: direct control of single-minded transcription by dorsal/ventral patterning genes.Gene Expr. 1998;7(3):171-89. Gene Expr. 1998. PMID: 9840810 Free PMC article.
-
The CNS midline cells and spitz class genes are required for proper patterning of Drosophila ventral neuroectoderm.Int J Dev Biol. 1999 Jul;43(4):305-15. Int J Dev Biol. 1999. PMID: 10470647
-
The CNS midline cells coordinate proper cell cycle progression and identity determination of the Drosophila ventral neuroectoderm.Dev Biol. 2000 Nov 15;227(2):307-23. doi: 10.1006/dbio.2000.9905. Dev Biol. 2000. PMID: 11071757
-
Drosophila single-minded gene and the molecular genetics of CNS midline development.J Exp Zool. 1992 Mar 1;261(3):234-44. doi: 10.1002/jez.1402610303. J Exp Zool. 1992. PMID: 1629656 Review.
-
Role of the midline glia and neurons in the formation of the axon commissures in the central nervous system of the Drosophila embryo.Ann N Y Acad Sci. 1991;633:142-59. doi: 10.1111/j.1749-6632.1991.tb15604.x. Ann N Y Acad Sci. 1991. PMID: 1789544 Review.
Cited by
-
Single cell cultures of Drosophila neuroectodermal and mesectodermal central nervous system progenitors reveal different degrees of developmental autonomy.Neural Dev. 2009 Aug 3;4:30. doi: 10.1186/1749-8104-4-30. Neural Dev. 2009. PMID: 19650920 Free PMC article.
-
Down syndrome-critical region contains a gene homologous to Drosophila sim expressed during rat and human central nervous system development.Proc Natl Acad Sci U S A. 1995 Sep 26;92(20):9191-5. doi: 10.1073/pnas.92.20.9191. Proc Natl Acad Sci U S A. 1995. PMID: 7568099 Free PMC article.
-
Specification of the Drosophila CNS midline cell lineage: direct control of single-minded transcription by dorsal/ventral patterning genes.Gene Expr. 1998;7(3):171-89. Gene Expr. 1998. PMID: 9840810 Free PMC article.
-
Two new members of the murine Sim gene family are transcriptional repressors and show different expression patterns during mouse embryogenesis.Mol Cell Biol. 1996 Oct;16(10):5865-75. doi: 10.1128/MCB.16.10.5865. Mol Cell Biol. 1996. PMID: 8927054 Free PMC article.
-
A comparison of midline and tracheal gene regulation during Drosophila development.PLoS One. 2014 Jan 20;9(1):e85518. doi: 10.1371/journal.pone.0085518. eCollection 2014. PLoS One. 2014. PMID: 24465586 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Molecular Biology Databases