Community-based prevalence profile of arboviral, rickettsial, and Hantaan-like viral antibody in the Nile River Delta of Egypt
- PMID: 8101432
- DOI: 10.4269/ajtmh.1993.48.776
Community-based prevalence profile of arboviral, rickettsial, and Hantaan-like viral antibody in the Nile River Delta of Egypt
Abstract
To determine the current prevalence of antibody to arboviruses, rickettsiae, and hantaan-like viruses, a survey was carried out in the Nile River Valley of Egypt, one of the principal foci of the 1977-1978 Rift Valley fever (RVF) outbreak. Blood specimens were obtained from 915 persons representing 190 study households. Enzyme immunoassay testing showed that the overall prevalence of IgG antibody was 4% to sand fly fever Sicilian (SFS), 2% to sandfly fever Naples (SFN), 15% to RVF, 20% to West Nile, and 4% to Hantaan (HTN) viruses. Antibody was demonstrated among 32% of the same study subjects to Coxiella burnetii, 58% to Rickettsia typhi, and 32% to R. conorii. The prevalence of agent-specific antibody tended to increase with age. Particularly notable was the low prevalence of RVF infection in children born after the height of the RVF outbreak. No detectable antibodies were found in the population less than seven years of age and in only 3% of those 7-12 years old. In contrast, 26% of the study population 13-19 years old, who were young children and infants at the time of the outbreak, were found to have RVF antibodies, suggesting that the level of intensity associated with transmission decreased considerably following the documented 1977-1978 outbreak. Geometric mean titers (GMT) ranged from 139 for C. burnetii to 1,305 for RVF, and did not vary significantly by age, except for high titers for RVF in the 20-49-year-old age group. A significant upward trend in GMT was also noted when antibody was detected in the specimen for more than one phlebovirus.(ABSTRACT TRUNCATED AT 250 WORDS)
Similar articles
-
The prevalence of arboviral, rickettsial, and Hantaan-like viral antibody among schoolchildren in the Nile river delta of Egypt.Trans R Soc Trop Med Hyg. 1992 Nov-Dec;86(6):677-9. doi: 10.1016/0035-9203(92)90189-j. Trans R Soc Trop Med Hyg. 1992. PMID: 1363163
-
Arthropod-borne viral infections associated with a fever outbreak in the northern province of Sudan.J Trop Med Hyg. 1994 Aug;97(4):228-30. J Trop Med Hyg. 1994. PMID: 8064945
-
Infections in an Alpine environment: antibodies to hantaviruses, leptospira, rickettsiae, and Borrelia burgdorferi in defined Italian populations.Am J Trop Med Hyg. 1993 Jan;48(1):20-5. doi: 10.4269/ajtmh.1993.48.20. Am J Trop Med Hyg. 1993. PMID: 8093990
-
Infection by certain arboviruses among workers potentially at risk of infection.J Egypt Public Health Assoc. 2001;76(3-4):169-82. J Egypt Public Health Assoc. 2001. PMID: 17216941
-
Seroepidemiology of selected arboviruses in febrile patients visiting selected health facilities in the lake/river basin areas of Lake Baringo, Lake Naivasha, and Tana River, Kenya.Vector Borne Zoonotic Dis. 2015 Feb;15(2):124-32. doi: 10.1089/vbz.2014.1686. Vector Borne Zoonotic Dis. 2015. PMID: 25700043 Free PMC article.
Cited by
-
First serological evidence of West Nile virus in human rural populations of Gabon.Virol J. 2010 Jun 17;7:132. doi: 10.1186/1743-422X-7-132. Virol J. 2010. PMID: 20565765 Free PMC article.
-
Cross-sectional study for determining the prevalence of Q fever in small ruminants and humans at El Minya Governorate, Egypt.BMC Res Notes. 2017 Oct 30;10(1):538. doi: 10.1186/s13104-017-2868-2. BMC Res Notes. 2017. PMID: 29084604 Free PMC article.
-
Epidemiology of Mosquito-Borne Viruses in Egypt: A Systematic Review.Viruses. 2022 Jul 20;14(7):1577. doi: 10.3390/v14071577. Viruses. 2022. PMID: 35891557 Free PMC article.
-
A Comprehensive Review of Common Bacterial, Parasitic and Viral Zoonoses at the Human-Animal Interface in Egypt.Pathogens. 2017 Jul 21;6(3):33. doi: 10.3390/pathogens6030033. Pathogens. 2017. PMID: 28754024 Free PMC article. Review.
-
Rickettsial agents in Egyptian ticks collected from domestic animals.Exp Appl Acarol. 2006;40(1):67-81. doi: 10.1007/s10493-006-9025-2. Epub 2006 Sep 27. Exp Appl Acarol. 2006. PMID: 17004028
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Research Materials
Miscellaneous