doi: 10.1136/adc.69.6.693.
Optimum use of a spacer device
Affiliations
- PMID: 8110296
- PMCID: PMC1029658
- DOI: 10.1136/adc.69.6.693
Item in Clipboard
Optimum use of a spacer device
Arch Dis Child.
1993 Dec.
Abstract
Nedocromil sodium given by the Fisonair spacer should be inhaled immediately. Multiple actuations into the spacer should be avoided. Delay of 20 seconds before sampling reduced the amount of drug available for inhalation in the respirable range by 81%. Placing two actuations into the spacer reduced the amount of drug available by 47%.
Similar articles
-
The effect of delay, multiple actuations and spacer static charge on the in vitro delivery of budesonide from the Nebuhaler.Br J Clin Pharmacol. 1995 Jul;40(1):76-8. doi: 10.1111/j.1365-2125.1995.tb04538.x. Br J Clin Pharmacol. 1995. PMID: 8527272 Free PMC article.
-
Comparison of nedocromil sodium and sodium cromoglycate administered by pressurized aerosol, with and without a spacer device in exercise-induced asthma in children.Eur Respir J. 1993 Apr;6(4):523-6. Eur Respir J. 1993. PMID: 8387933 Clinical Trial.
-
Improvement in sodium cromoglycate delivery from a spacer device by use of an antistatic lining, immediate inhalation, and avoiding multiple actuations of drug.Thorax. 1993 Jun;48(6):603-6. doi: 10.1136/thx.48.6.603. Thorax. 1993. PMID: 8346488 Free PMC article.
-
The clinical efficacy of inhaled nedocromil sodium (Tilade) in the treatment of asthma.Eur Respir J. 1993 Jan;6(1):35-41. Eur Respir J. 1993. PMID: 8381089 Review.
-
[Anti-inflammatory effects of cromones in asthma].Allerg Immunol (Paris). 1995 Feb;27(2):50-4. Allerg Immunol (Paris). 1995. PMID: 7786345 Review. French.
Cited by
-
A comparative analysis of the particle size output of beclomethasone diproprionate, salmeterol xinafoate and fluticasone propionate metered dose inhalers used with the Babyhaler, Volumatic and Aerochamber spacer devices.Br J Clin Pharmacol. 1999 Apr;47(4):357-60. doi: 10.1046/j.1365-2125.1999.00900.x. Br J Clin Pharmacol. 1999. PMID: 10233197 Free PMC article.
-
The effect of delay, multiple actuations and spacer static charge on the in vitro delivery of budesonide from the Nebuhaler.Br J Clin Pharmacol. 1995 Jul;40(1):76-8. doi: 10.1111/j.1365-2125.1995.tb04538.x. Br J Clin Pharmacol. 1995. PMID: 8527272 Free PMC article.
-
The challenge of delivering therapeutic aerosols to asthma patients.ISRN Allergy. 2013 Aug 5;2013:102418. doi: 10.1155/2013/102418. eCollection 2013. ISRN Allergy. 2013. PMID: 23984095 Free PMC article.
-
Usefulness of Nonvalved Spacers for Administration of Inhaled Steroids in Young Children with Recurrent Wheezing and Risk Factors for Asthma.Can Respir J. 2018 Sep 3;2018:3095647. doi: 10.1155/2018/3095647. eCollection 2018. Can Respir J. 2018. PMID: 30250631 Free PMC article. Clinical Trial.
-
Nebuliser therapy in childhood.Thorax. 1997 Apr;52 Suppl 2(Suppl 2):S78-88. doi: 10.1136/thx.52.2008.s78. Thorax. 1997. PMID: 9155859 Free PMC article. Review. No abstract available.
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources