Review
doi: 10.1016/0306-3623(93)90412-q.
Gravidin: an endogenous inhibitor of phospholipase A2
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- PMID: 8112500
- DOI: 10.1016/0306-3623(93)90412-q
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Review
Gravidin: an endogenous inhibitor of phospholipase A2
Gen Pharmacol.
1993 Nov.
Abstract
Gravidin is a recently discovered protein inhibitor of phospholipase A2 and therefore prostaglandin synthesis. Transformed or rapidly growing cells are unaffected by gravidin, but in slow-growing cells arachidonate release is inhibited. Gravidin may play a physiological role in pregnancy maintenance. This review summarizes our current knowledge of the properties and activity of gravidin.
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