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. 1993 Nov 12;162(1-2):81-4.
doi: 10.1016/0304-3940(93)90565-3.

Psychological stress increases serotonin release in the rat amygdala and prefrontal cortex assessed by in vivo microdialysis

H Kawahara  1 , M Yoshida, H Yokoo, M Nishi, M Tanaka
Affiliations

Psychological stress increases serotonin release in the rat amygdala and prefrontal cortex assessed by in vivo microdialysis

H Kawahara et al. Neurosci Lett. .

Abstract

The effects of psychological stress on serotonin (5-HT) release were studied in the basolateral amygdaloid nucleus and the prefrontal cortex in conscious rats with in vivo microdialysis. Psychological stress, wherein emotional factors were predominantly involved, significantly increased extracellular 5-HT levels in these two areas. These findings suggest that activation of serotonergic neurons in these brain regions is involved in the emotional and/or cognitive states in animals.

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