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Clinical Trial
. 1993;29(3):371-4.

Vitamin E in tardive dyskinesia: time course of effect after placebo substitution

Affiliations
  • PMID: 8121964
Clinical Trial

Vitamin E in tardive dyskinesia: time course of effect after placebo substitution

L A Adler et al. Psychopharmacol Bull. 1993.

Abstract

Alpha-tocopherol (vitamin E) has been found to be effective in the treatment of tardive dyskinesia (TD). Studies to date have been short in duration and have not found long-term carryover effects of vitamin E. The present study examined the persistence of the effects of vitamin E after longer term (36-week) treatment was discontinued. Vitamin E significantly improved TD over this period. However, the effects of vitamin E persisted so that TD scores approached baseline only after 12 weeks of placebo substitution.

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