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. 1993 Dec;21(6):844-7.
doi: 10.1177/0310057X9302100617.

An appraisal of techniques for administration of gaseous nitric oxide

J Tibballs  1 , M Hochmann, B Carter, A Osborne
Affiliations

An appraisal of techniques for administration of gaseous nitric oxide

J Tibballs et al. Anaesth Intensive Care. 1993 Dec.

Abstract

Gaseous nitric oxide (NO) is a potent selective pulmonary vasodilator. When mixed with O2 for more than 10-15 minutes it forms toxic amounts of nitrogen dioxide (NO2). We describe two techniques to administer 20 parts per million (ppm) during mechanical ventilation. A technique using flows of NO and O2 at low pressure to drive a Siemens Servo 900C ventilator provided a constant inspired concentration of NO. Another technique in which NO was added to the inspiratory limb of a Siemens Servo 900C ventilator driven by high pressure oxygen provided a highly variable concentration (9-53 ppm) of inspired NO.

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Comment in

  • Nitric oxide administration.
    Moors AH, Pickett JA, Mahmood N, Latimer RD, Oduro A. Moors AH, et al. Anaesth Intensive Care. 1994 Jun;22(3):310-2. Anaesth Intensive Care. 1994. PMID: 8085638 No abstract available.

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