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. 1994 Jan;59(1):48-52.
doi: 10.1111/j.1751-1097.1994.tb05000.x.

Early alterations of actin in cultured human keratinocytes and fibroblasts exposed to long-wavelength radiations. Possible involvement in the UVA-induced perturbations of endocytotic processes

M Djavaheri-Mergny  1 , M T Pieraggi, C Mazière, R Santus, A Lageron, R Salvayre, L Dubertret, J C Mazière
Affiliations

Early alterations of actin in cultured human keratinocytes and fibroblasts exposed to long-wavelength radiations. Possible involvement in the UVA-induced perturbations of endocytotic processes

M Djavaheri-Mergny et al. Photochem Photobiol. 1994 Jan.

Abstract

Exposure of cultured MRC5 human fibroblasts or NCTC 2544 human keratinocytes to mild doses of ultraviolet A (UVA: 320-400 nm) radiations markedly decreased the actin reactivity with fluorescein-labeled phalloidin. This indicates a change in the degree of polymerization of actin and thus in the organization of actin filaments. Such a phenomenon might be involved in the previously reported UVA-induced inhibition of specific and nonspecific endocytotic processes.

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