Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1975 Dec 1;53(23):1133-4.
doi: 10.1007/BF01614283.

[Haemodynamic effects of furosemide and ethacrynic acid (author's transl)]

[Article in German]
K E Schenk, G Biamino, R Schröder
Clinical Trial

[Haemodynamic effects of furosemide and ethacrynic acid (author's transl)]

[Article in German]
K E Schenk et al. Klin Wochenschr. .

Abstract

The haemodynamic effects of intravenous injections of furosemide and ethacrynic acid were studied in 12 patients during rest and exercise. Cardiac output, heart rate and arterial blood pressure showed no significant changes after injection of furosemide or ethacrynic acid. Few minutes after injection of furosemide there were significant falls of pulmonary artery diastolic pressure and right atrial pressure, whereas no changes were seen after injection of ethacrynic acid. This initial effect of furosemide apparently is of primarily vascular origin, causing an increased peripheral venous capacitance. Ethacrynic acid failed to exhibit any direct vascular effect.

PubMed Disclaimer

References

    1. N Engl J Med. 1968 Jul 18;279(3):115-22 - PubMed
    1. Circulation. 1974 Jan;49(1):136-43 - PubMed
    1. Can J Physiol Pharmacol. 1973 Mar;51(3):183-9 - PubMed
    1. N Engl J Med. 1973 May 24;288(21):1087-90 - PubMed
    1. Verh Dtsch Ges Inn Med. 1975;81:303-6 - PubMed