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. 1994 Feb;60(1):37-40.
doi: 10.1055/s-2006-959404.

In vitro inhibition of cyclooxygenase and 5-lipoxygenase by alkamides from Echinacea and Achillea species

B Müller-Jakic  1 , W Breu, A Pröbstle, K Redl, H Greger, R Bauer
Affiliations

In vitro inhibition of cyclooxygenase and 5-lipoxygenase by alkamides from Echinacea and Achillea species

B Müller-Jakic et al. Planta Med. 1994 Feb.

Abstract

Polyunsaturated alkamides isolated from Achillea species, Echinacea angustifolia DC., Anacyclus pyrethrum (L.) Link, and Aaronsohnia pubescens (Desf.) Bremer & Humphries, (Compositae) were shown to possess inhibitory activity in in vitro cyclooxygenase (sheep seminal microsomes) and 5-lipoxygenase (porcine leukocytes) assays. Activity appeared to depend on the particular structure of the alkamides.

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