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. 1994 Apr;191(1):257-62.
doi: 10.1148/radiology.191.1.8134584.

Use of quantitative CT to predict postoperative lung function in patients with lung cancer

M T Wu  1 , J M Chang, A A Chiang, J Y Lu, H K Hsu, W H Hsu, C F Yang
Affiliations

Use of quantitative CT to predict postoperative lung function in patients with lung cancer

M T Wu et al. Radiology. 1994 Apr.

Abstract

Purpose: To evaluate the effectiveness of quantitative computed tomography (CT) for predicting postoperative lung function in patients with lung cancer.

Materials and methods: Preoperative spirometry and conventional CT of the chest were performed in 38 patients. A postprocessing CT program was applied to quantitate the volume of whole-lung parenchyma with attenuations of -500 to -910 HU; this was defined as total functional lung volume (TFLV). The regional functional lung volume (RFLV) of the lobes or lung to be resected was quantitated separately. CT-predicted postoperative forced expiratory volume in 1 second (FEV1) and forced vital capacity (FVC) were derived by multiplying the preoperative spirometry values by (1 - RFLV/TFLV).

Results: CT-predicted values correlated well with postoperatively measured results (FEV1: r = .93, P < .001; FVC: r = .86, P < .001) in patients who underwent pneumonectomy or lobectomy, regardless of the patient's preoperative ventilation status.

Conclusion: This method is effective in the prediction of postoperative FEV1 and FVC in patients undergoing pulmonary resection.

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