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Clinical Trial
. 1993 Dec;44(4):331-2.

Comparison of ivermectin and benzyl benzoate for treatment of scabies

P Glaziou  1 , J L Cartel, P Alzieu, C Briot, J P Moulia-Pelat, P M Martin
Affiliations
  • PMID: 8134777
Clinical Trial

Comparison of ivermectin and benzyl benzoate for treatment of scabies

P Glaziou et al. Trop Med Parasitol. 1993 Dec.

Abstract

A randomized investigator-blinded trial of oral ivermectin 100 micrograms/kg single dose vs. benzyl benzoate 10% application in the treatment of scabies, was conducted in 1992 in French Polynesia. In total, 44 patients aged 5-56 years were included in the study: 23 in the group ivermectin (IVER) and 21 in the group benzyl benzoate (BB). At day 30 after treatment, the cumulative recovery rates were 70% (16/23) in the group IVER, and 48% (10/21) in the group BB, 95% confidence intervals 51-87% and 29-70% respectively. The rates of recovery were greater in the group IVER at day 7, 14 and 30, but the difference was not statistically significant. Our results show that oral ivermectin is a valuable alternative to benzyl benzoate local treatment.

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