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Clinical Trial
. 1975 Nov;30(5):298-305.
doi: 10.1111/j.1398-9995.1975.tb00206.x.

ICI 74,917: a new anti-allergic drug administered by pressurised aerosol

N Mygind, J Thomsen
Clinical Trial

ICI 74,917: a new anti-allergic drug administered by pressurised aerosol

N Mygind et al. Acta Allergol. 1975 Nov.

Abstract

Ten patients with allergic rhinitis were challenged intranasally with allergen before, and half an hour, 2 hours and 4 hours after intranasal administration of placebo, disodium cromoglycate powder and an aerosol containing ICI 74,917, a new compound with anti-allergic action. ICI 74,917 had a maximum protective effect after half an hour, but was significantly better than placebo 2 hours after nasal use. The effect was significantly better than that of disodium cromoglycate powder. The results will encourage studies of ICI 74,917 in the treatment of allergic rhinitis.

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