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. 1975 Dec 31;254(3):275-80.
doi: 10.1007/BF00557969.

Serological studies on the carbohydrate moiety of human tyrosinase

W P Herrmann, G Uhlenbruck

Serological studies on the carbohydrate moiety of human tyrosinase

W P Herrmann et al. Arch Dermatol Res (1975). .

Abstract

1. Human tyrosinase is a glycoprotein containing N-acetylneuraminic acid. 2. The terminal neuraminic acid groups are linked to D-galactose. 3. In addition, human tyrosinase reacts strongly with concanavalin A. This finding indicates that the carbohydrate chain of human tyrosinase contains D-mannose. 4. The data presented here suggest that the carbohydrate moiety of human tyrosinase is linked to the protein core in an alkali-stable form. 5. Alkali-labile carbohydrate chains which occur predominantly in membrane bound glycoproteins could not be demonstrated serologically.

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References

    1. Arch Dermatol Forsch. 1971;241(1):65-74 - PubMed
    1. Annu Rev Biochem. 1973;42(0):541-74 - PubMed
    1. Vox Sang. 1975;28(2):133-48 - PubMed
    1. Arch Dermatol Forsch. 1972;243(4):341-5 - PubMed
    1. Arch Dermatol Forsch. 1975;252(3):211-6 - PubMed