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Review
. 1993 Sep;1(6):221-8.
doi: 10.1016/0966-842x(93)90136-f.

Hepatitis B virus replication

M Nassal  1 , H Schaller
Affiliations
Review

Hepatitis B virus replication

M Nassal et al. Trends Microbiol. 1993 Sep.

Abstract

Hepatitis B virus (HBV) is the causative agent of B-type hepatitis in humans and the prototypic member of the hepadnaviruses. It is a small enveloped DNA virus that replicates via reverse transcription. Although hepadnaviruses are similar to retroviruses in basic life cycle and genome organization, recent studies have revealed several unique hepadnaviral strategies that optimize exploitation of their extremely small circular DNA genomes.

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