doi: 10.1507/endocrj1954.22.457.
Stimulation of human prolactin secretion by sulpiride
- PMID: 813995
- DOI: 10.1507/endocrj1954.22.457
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Stimulation of human prolactin secretion by sulpiride
Endocrinol Jpn.
1975 Oct.
Free article
Abstract
Intramuscular injection of 100 mg of sulpiride significantly raised plasma human prolactin (hPRL) levels in all of 7 normal subjects examined. The mean (+SE) peak value was 78.0 +/- 16.6 ng/ml, which was observed 30 min after the injection. Daily administration of sulpiride (50 mg tid po) raised plasma hPRL levels in all 7 patients with peptic ulcer, with peak values obtained within 2 weeks. Lactation occurred in 2 of these patients. It is concluded that sulpiride stimulates hPRL secretion in man.
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