doi: 10.1016/s0140-6736(78)91573-8.
Haemolytic-uraemic syndrome: deficiency of plasma factor(s) regulating prostacyclin activity?
- PMID: 81415
- DOI: 10.1016/s0140-6736(78)91573-8
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Haemolytic-uraemic syndrome: deficiency of plasma factor(s) regulating prostacyclin activity?
Lancet.
.
Abstract
It is suggested that patients with the haemolytic-uraemic syndrome and related disorders (such as thrombotic thrombocytopenic purpura) lack a plasma factor which stimulates prostacyclin (P.G.I2) activity. Normal plasma would supply the missing factor and is a rational treatment for some life-threatening symptoms (thrombocytopenia, haemolytic anaemia, hypertension) of this syndrome.
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