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Review
. 1993 Apr;1(1):32-4.
doi: 10.1016/0966-842x(93)90022-j.

Subversion of host immune responses by viral superantigens

H Acha-Orbea  1 , H R MacDonald
Affiliations
Review

Subversion of host immune responses by viral superantigens

H Acha-Orbea et al. Trends Microbiol. 1993 Apr.

Abstract

Recent experiments with mouse mammary tumor virus indicate that expression of a virally encoded superantigen by B cells and its subsequent recognition by T cells are essential steps for amplification of infection and virus transmission. Preliminary results suggest that superantigens may also be expressed during retroviral infection in humans.

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