[TPHA test. Comparison with classical lues reactions and the FTA-ABS test (author's transl)]

Abstract

1. 227 sera from a mixed group of patients were investigated by the TPHA test, FTA-ABS test, the complement fixation reaction with cardiolipin and pallida antigens, the Meinicke test II and the VDRL test, and compared. 2. 124 sera with a diagnosis of "latent seropositive syphilis" were compared in the same way. The TPHA, FTA-ABS and VDRL tests were in very good agreement with a high specificity and sensitivity, so that all 3 methods are suitable for routine diagnosis. 3. A change in the diagnostic methods for lues is discussed in the light of our own results and those published in the literature and the fact that no unclarified cases remain after using the TPHA and the FTA-ABS tests.