Review
doi: 10.1093/rheumatology/15.1.1.
Auto-immune disease
- PMID: 814605
- DOI: 10.1093/rheumatology/15.1.1
Item in Clipboard
Review
Auto-immune disease
Rheumatol Rehabil.
1976 Feb.
Abstract
Auto-immune disease may result from the interaction of the genetic load of the individual, modification of self-tissue antigens by environmental agents such as virus or drugs and abnormalities of the immunological system itself such as the loss of controlling or suppressor T cells with age. In the majority of people the outcome is tolerance, maintenance of normal tissue architecture and function. In the unfortunate few the outcome is auto-immune disease, that is, failure to recognize "self".
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