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. 1994;15(1):1-6.
doi: 10.1159/000217867.

Use of CA 19-9 in the early detection of recurrences in colorectal cancer: comparison with CEA

X Filella  1 , R Molina, J M Piqué, J C Garcia-Valdecasas, J J Grau, F Novell, E Astudillo, A de Lacy, M Daniels, A M Ballesta
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Free article

Use of CA 19-9 in the early detection of recurrences in colorectal cancer: comparison with CEA

X Filella et al. Tumour Biol. 1994.
Free article

Abstract

The serum levels of CA 19-9 were determined in the follow-up of 370 patients with colorectal cancer and compared with CEA. An increase in CA 19-9 preceded clinical diagnosis of recurrence in 25% of 72 patients. The mean time between the rise in CA 19-9 and clinical diagnosis of relapse was 3.7 months (median 3). Sensitivity of CA 19-9 in the early diagnosis of recurrence was much lower than that obtained for CEA (75%). Only 1 patient had elevated CA 19-9 levels and normal CEA.

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