Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1994 Apr;89(4):497-502.

Are esophageal symptoms reflux-related? A study of different scoring systems in a cohort of patients with heartburn

B T Johnston  1 , J S Collins, R J McFarland, A H Love
Affiliations
  • PMID: 8147349
Comparative Study

Are esophageal symptoms reflux-related? A study of different scoring systems in a cohort of patients with heartburn

B T Johnston et al. Am J Gastroenterol. 1994 Apr.

Abstract

Objective: To assess three different methods of correlating symptoms with episodes of acid reflux in gastroesophageal reflux disease.

Methods: One hundred and one consecutive patients with heartburn were recruited. Patients were divided into those with and those without endoscopic esophagitis. Three different symptom indices were used, one of which was based on the binomial formula. It took into account not only the ratio of acid-related symptoms to all symptoms, but also the quantity of acid reflux.

Results: There was complete agreement between all three indices in 78% of the patients. All three indices were positive significantly more often (p < 0.001) in patients with esophagitis than in patients with no esophagitis.

Conclusions: All indices gave similar results. The binomial symptom index offers theoretical advantages, but a prospective study of response to acid suppression would be required to evaluate further its merits.

PubMed Disclaimer

Publication types

Substances