Combined allergy to human seminal plasma and latex: case report and review of the literature

Abstract

The case is reported of a young atopic woman with combined Type I and possible Type IV allergy to human seminal plasma, as well as Type-I allergy to latex. Clinical symptoms were swelling and a burning sensation on the vulva and in the vulvovaginal area during or after coitus, followed by vesiculation, lichenification and the development of generalized eczema. Diagnosis was confirmed by investigation (RAST, prick testing, histology). Literature on the subject is reviewed.