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Review
. 1994 Feb;2(2):52-6.
doi: 10.1016/0966-842x(94)90126-0.

Mechanisms of virus uncoating

U F Greber  1 , I Singh, A Helenius
Affiliations
Free article
Review

Mechanisms of virus uncoating

U F Greber et al. Trends Microbiol. 1994 Feb.
Free article

Abstract

In a virus particle, the genome is highly condensed and protected by proteins and membrane bilayers. Before it can be replicated in a new host cell, uncoating must take place. Recent studies on enveloped and nonenveloped animal viruses indicate that uncoating occurs through complex, multistep processes triggered by virus-host-cell interactions.

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