Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1994 Jan;241(3):170-4.
doi: 10.1007/BF00868345.

Amyloid-P-component-like immunoreactivity in beta/A4-immunoreactive deposits in Alzheimer-type dementia brains

M Kimura  1 , H Arai, T Takahashi, N Iwamoto
Affiliations

Amyloid-P-component-like immunoreactivity in beta/A4-immunoreactive deposits in Alzheimer-type dementia brains

M Kimura et al. J Neurol. 1994 Jan.

Abstract

An immunohistochemical study using the mirror-image technique was performed in order to establish whether amyloid P component is involved in the mechanism of deposition of amyloid fibrils in senile plaques (SPs) in Alzheimer-type dementia (ATD). Ninety percent of beta/A4 protein-immunoreactive SPs were also stained by the anti-amyloid P component immunohistochemistry, and this applied to all of the diffuse, primitive and classical types of beta/A4 deposits. These findings may suggest an involvement of amyloid P component in the formation of amyloid fibrils in senile plaques in ATD brains.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Brain Res. 1991 May 10;548(1-2):349-52 - PubMed
    1. Proc Natl Acad Sci U S A. 1977 Feb;74(2):739-43 - PubMed
    1. J Neurol. 1983;229(2):69-77 - PubMed
    1. Science. 1987 Jul 3;237(4810):77-80 - PubMed
    1. Lab Invest. 1988 Apr;58(4):454-8 - PubMed

MeSH terms

Substances

LinkOut - more resources