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Review
. 1994 Feb;6(1):69-73.
doi: 10.1016/0955-0674(94)90118-x.

Structure, function and regulation of cytoplasmic dynein

Affiliations
Review

Structure, function and regulation of cytoplasmic dynein

T A Schroer. Curr Opin Cell Biol. 1994 Feb.

Abstract

Molecular cloning studies have provided valuable structural information about the different subunits of cytoplasmic dynein and their relationships to their axonemal dynein counterparts. Recent unexpected findings regarding the role of this enzyme in mitosis have emerged from mutational analyses and microinjection experiments, while studies of organelle transport in vivo have revealed clues to mechanisms for physiological regulation of dynein activity.

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