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Review
. 1994 Feb;6(1):82-6.
doi: 10.1016/0955-0674(94)90120-1.

Actin-dependent motile forces and cell motility

L P Cramer  1 , T J Mitchison, J A Theriot
Affiliations
Review

Actin-dependent motile forces and cell motility

L P Cramer et al. Curr Opin Cell Biol. 1994 Feb.

Abstract

Force arising from actin polymerization and myosin activity drives a number of different actin-based cell movements. Several new reports support previous data suggesting that actin polymerization drives lamellipodial protrusion and bacterial propulsion, and one report describes a more indirect role for actin assembly in axonal elongation. The major new findings of the past year concerning possible motility roles for myosin describe myosin-driven protrusion of cell margins.

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