[The effect of acetylcholine on neuromuscular transmission in the fatigued rat diaphragm with blocked acetylcholinesterase]
[Article in
Russian]
- PMID: 8167666
Item in Clipboard
[The effect of acetylcholine on neuromuscular transmission in the fatigued rat diaphragm with blocked acetylcholinesterase]
[Article in
Russian]
Fiziol Zh Im I M Sechenova.
1993 Oct.
Abstract
The rat phrenic-diaphragm preparations with amine-inhibited acetylcholinesterase were fatigued by rhythmical nerve stimulation. Tetanization of the nerve by bursts of stimuli 20/sec led to a long-term recovery of muscle contractions of the fatigued muscles. The recovery was completely abolished by tubocurarine and partially--by atropine. Acetylcholine bathing simulated the effect of tetanization. Probable mechanisms of this phenomenon are discussed.
Similar articles
-
[Restoration of neuromuscular transmission in the rat diaphragm after the action of an organophosphorus inhibitor of acetylcholinesterase by using curare].Fiziol Zh SSSR Im I M Sechenova. 1988 Dec;74(12):1751-8. Fiziol Zh SSSR Im I M Sechenova. 1988. PMID: 2854078 Russian.
-
The generation of nerve and muscle repetivie activity in the rat phrenic nerve-diaphragm preparation following inhibition of cholinesterase by ecothiopate.Br J Pharmacol. 1977 May;60(1):45-53. doi: 10.1111/j.1476-5381.1977.tb16745.x. Br J Pharmacol. 1977. PMID: 195659 Free PMC article.
-
[The effect of exogenous acetylcholine on the effectiveness of neuromuscular transmission in rat diaphragm fatigue].Biull Eksp Biol Med. 1994 Nov;118(11):457-9. Biull Eksp Biol Med. 1994. PMID: 7888638 Russian. No abstract available.
-
Physiology and biology of neuromuscular transmission in health and disease.J Crit Care. 2009 Mar;24(1):5-10. doi: 10.1016/j.jcrc.2008.08.002. Epub 2009 Jan 17. J Crit Care. 2009. PMID: 19272533 Review.
-
[The mechanism of pessimum at the myoneural junction].Nerv Sist. 1975;15:17-35. Nerv Sist. 1975. PMID: 175305 Review. Russian. No abstract available.