[The effect of noradrenaline, acetylcholine and their blockers on cortical neuronal activity in goal-directed behavior]

Abstract

Neurochemical cellular mechanisms of central organization of the consecutive stages of formation of a goal-directed behavioural act were studied in cats by means of microiontophoretic application of biologically active substances. Chemical characteristics of single cortical neurons varied at different stages of behavioural act. Dynamics of spike activity at these stages changed in opposite directions during application of neurotransmitters and their antagonists. The differences were more expressed during propranolol and atropine than during noradrenaline and acetylcholine application.