Review
doi: 10.1016/0167-5699(94)90155-4.
Complement factor H and related proteins: an expanding family of complement-regulatory proteins?
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- PMID: 8172644
- DOI: 10.1016/0167-5699(94)90155-4
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Review
Complement factor H and related proteins: an expanding family of complement-regulatory proteins?
Immunol Today.
1994 Mar.
Abstract
Recently, several factor-H-related molecules have been identified in humans and mice, initiating new interest in this group of serum proteins. Although no complement-regulatory activity has been demonstrated yet for the human factor-H-related proteins, the immunological and structural similarities to factor H suggest overlapping functions. Here, Peter Zipfel and Christine Skerka review these similarities and suggest a new nomenclature to identify members of the factor-H-related family.
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