Review
Brain-derived neurotrophic factor (BDNF): role in neuronal development and survival
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Review
Brain-derived neurotrophic factor (BDNF): role in neuronal development and survival
Folia Morphol (Warsz).
1993.
Abstract
In 1989 Leitbrock et al. reported the full primary structure of brain-derived neurotrophic factor. The messenger RNA for BDNF was found predominantly in the central nervous system, and the sequence of protein indicated its structural relation to NGF. BDNF belongs to a larger family of neurotrophic molecules. It stimulates the neurite outgrowth and supports neuronal survival.
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