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Review
. 1993;52(4):173-81.

Brain-derived neurotrophic factor (BDNF): role in neuronal development and survival

Affiliations
  • PMID: 8175070
Review

Brain-derived neurotrophic factor (BDNF): role in neuronal development and survival

W Woźniak. Folia Morphol (Warsz). 1993.

Abstract

In 1989 Leitbrock et al. reported the full primary structure of brain-derived neurotrophic factor. The messenger RNA for BDNF was found predominantly in the central nervous system, and the sequence of protein indicated its structural relation to NGF. BDNF belongs to a larger family of neurotrophic molecules. It stimulates the neurite outgrowth and supports neuronal survival.

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