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Case Reports
. 1994 Mar;153(3):181-3.
doi: 10.1007/BF01958981.

Guillain-Barré syndrome associated with IgM anti-GM1 antibody following Campylobacter jejuni enteritis

K Sugita  1 , M Ishii, J Takanashi, H Niimi, N Yuki
Affiliations
Case Reports

Guillain-Barré syndrome associated with IgM anti-GM1 antibody following Campylobacter jejuni enteritis

K Sugita et al. Eur J Pediatr. 1994 Mar.

Abstract

We report a 4-year-old girl diagnosed as having Guillain-Barré syndrome after infection by Penner serotype 19 of Campylobacter jejuni. The patient had the HLA-B35 antigen. Neurological examination revealed distal-dominant weakness and intact sensation. Serial electrophysiological studies indicated that the predominant process was axonal degeneration involving motor nerves. An enzyme-linked immunosorbent assay revealed the presence of high titres of serum IgM antibodies to gangliosides GM1 and GM2. The IgM auto-antibody titres decreased concurrently with the clinical course of the illness and no switching from IgM to IgG secretion took place.

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